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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
10.61
Human Site:
T348
Identified Species:
17.95
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
T348
P
P
A
S
S
A
M
T
H
L
S
G
H
S
R
Chimpanzee
Pan troglodytes
XP_509441
819
90122
P308
H
T
S
R
T
E
D
P
F
I
Q
P
T
D
F
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
Dog
Lupus familis
XP_546925
857
93734
T348
P
P
A
S
S
G
V
T
H
L
S
G
H
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
S348
P
S
P
A
S
S
S
S
S
S
G
M
T
P
H
Rat
Rattus norvegicus
Q6AXT8
471
49872
K10
F
Q
H
R
P
G
G
K
T
G
S
G
G
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
Q348
L
P
P
S
P
L
L
Q
V
S
G
T
L
A
H
Frog
Xenopus laevis
NP_001084764
548
60887
L87
G
K
T
S
S
C
H
L
S
I
D
A
S
L
T
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
S341
L
L
S
S
L
P
L
S
T
E
L
P
S
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
P343
P
Q
M
Q
Q
S
L
P
V
G
M
G
N
Q
Q
Honey Bee
Apis mellifera
XP_394429
1014
115124
T466
M
E
I
Q
T
V
L
T
P
V
Q
N
Q
V
Q
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
L351
S
A
S
S
S
A
S
L
H
Q
M
Q
V
A
Q
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
A464
G
Q
Q
N
I
F
S
A
Q
P
P
Q
N
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
S562
P
A
A
A
S
K
P
S
E
Q
L
Q
H
S
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
0
0
80
N.A.
13.3
13.3
N.A.
N.A.
13.3
13.3
6.6
N.A.
13.3
6.6
26.6
0
P-Site Similarity:
100
20
0
93.3
N.A.
33.3
13.3
N.A.
N.A.
26.6
20
26.6
N.A.
40
33.3
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
22
15
0
15
0
8
0
0
0
8
0
15
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
8
0
0
8
0
% D
% Glu:
0
8
0
0
0
8
0
0
8
8
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
8
0
0
8
0
0
0
0
0
8
% F
% Gly:
15
0
0
0
0
15
8
0
0
15
15
29
8
0
0
% G
% His:
8
0
8
0
0
0
8
0
22
0
0
0
22
0
15
% H
% Ile:
0
0
8
0
8
0
0
0
0
15
0
0
0
0
8
% I
% Lys:
0
8
0
0
0
8
0
8
0
0
0
0
0
0
0
% K
% Leu:
15
8
0
0
8
8
29
15
0
15
15
0
8
15
0
% L
% Met:
8
0
8
0
0
0
8
0
0
0
15
8
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
8
15
8
0
% N
% Pro:
36
22
15
0
15
8
8
15
8
8
8
15
0
8
8
% P
% Gln:
0
22
8
15
8
0
0
8
8
15
15
22
8
8
22
% Q
% Arg:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
15
% R
% Ser:
8
8
22
43
43
15
22
22
15
15
22
0
15
15
0
% S
% Thr:
0
8
8
0
15
0
0
22
15
0
0
8
15
8
8
% T
% Val:
0
0
0
0
0
8
8
0
15
8
0
0
8
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _